Figures
↓ Figure 1. Appearance of the left breast upon patient's admission.
↓ Figure 2. Left axillary lymph node, which appeared plump with an indistinct hilum and unclear corticomedullary differentiation.
↓ Figure 3. The image demonstrated edema and skin thickening in the left breast, with posterior acoustic attenuation, an indistinct glandular boundary, and disorganized echogenicity. Visualization of the glandular tissue, deep fascia, and pectoralis major muscle was poor.
↓ Figure 4. Multiple nodular T2WI hyperintense lesions were observed within the left breast, showing progressive enhancement.
↓ Figure 5. (a)The left breast was enlarged, containing multiple ill-defined nodular soft tissue lesions that demonstrated increased FDG metabolism. (b)Axial CT scan revealed the status of the lesion. The PET scan showed enhancement of the lesion. FDG: fluorodeoxyglucose; PET: positron emission tomography; CT: computed tomography.
↓ Figure 6. PET-CT revealed multiple osteolytic lesions with abnormally increased FDG metabolism in the bones throughout the body (axial skeleton and proximal appendicular skeleton), suggestive of widespread bone metastases. (a) Sagittal plane, showing the lesion. (b) Frontal plane, showing the lesion. PET-CT: positron emission tomography-computed tomography; FDG: fluorodeoxyglucose.
↓ Figure 7. Histopathological section. Tumor cells were diffusely distributed in a mixed pattern of round, polygonal, irregular, and spindle shapes, with prominent nucleoli and significant nuclear atypia (H&E staining, × 200). H&E: hematoxylin and eosin.
↓ Figure 8. Histopathological sections (H&E staining, × 200). Round, oval, and spindle-shaped tumor cells were arranged in nests and cords. H&E: hematoxylin and eosin.
↓ Figure 9. Immunohistochemical staining results (breast resection specimen, × 200). (a) Pan-cytokeratin (CKpan). (b) E-cadherin (E-cad). (c) GATA-3. (d) Vimentin. CKpan (3+), E-cad (+), GATA-3 (+), vimentin (3+), core needle biopsy revealed an epithelial neoplasm consistent with metaplastic carcinoma.
