Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 17, Number 9, September 2026, pages 470-481


Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop: A Case Series

Figures

↓  Figure 1. The location of virtual points on the shoe (a) and barefoot (b).
Figure 1.
↓  Figure 2. Plot of the toe clearance for participants 1 to 4 (baseline) using the tip virtual marker or digit 5 for participant 1, who was barefoot. The black line represents the mean of the toe clearance pattern from a sample of 10 gait trials of data, out of the 25 collected for each participant. The toe clearance graphs were normalized to 100% of the swing phase.
Figure 2.
↓  Figure 3. Plot of change in minimal toe clearance subjects 1–4 from baseline through mid-test point to post test.
Figure 3.

Tables

↓  Table 1. Patient Characteristics
 
Subject NumberYear of strokeAffected side (L/R)EthnicityAge (years)Sex (M/F)Weight (kg)Height (m)Past medical history
L: left; R: right; M: male; F: female; m: meters; kg: kilograms.
12010LBlack/African American58F68.041.75Bowel and bladder irregularities, allergies, vascular clots
22007LBlack/African American66M105.911.69Hypertension, diabetes
32020LBlack/African American36M68.491.69Nerve disease/disorder, speech/communication deficits, paresthesia
42022RBlack/African American42M92.991.68

 

↓  Table 2. Minimum or Maximum Toe Clearance and Joint Angle Data at Minimum Toe Clearance for All Four Participants Across All Three Testing Periods
 
SubjectMTC/MAX L1 (cm) SDMTC/MAX L2 (cm) SDMTC/MAX M1 (cm) SDMTC/MAX M2 (cm) SDMTC/MAX tip (cm) SDMean of lowest MTC values across trials (cm) SDPercentage of non-MTC for lowest MTC/MAX trials (%)Ankle joint angle at lowest MTC/MAX (°) SDKnee joint angle at lowest MTC/MAX (°) SDHip joint angle at lowest MTC/MAX (°) SDStance hip joint angle at lowest MTC/MAX (°) SD
Only the point with the lowest mean value is reported when all toe clearances are maximums, and other points are reported as non-MTC. Negative joint angles at the ankle = plantarflexion; knee = flexion; swing hip = extension; and stance hip = abduction. SD: standard deviation; non-MTC: when the toe clearance graph does not have a minimum in the mid-swing phase of the gait cycle; NA: not applicable.
Baseline
  11.68 (0.59)Non-MTCNon-MTCNon-MTCNon-MTC1.68 (0.59)100−14.72 (1.54)−28.84 (2.34)22.75 (1.99)−6.02 (1.38)
  2−0.26 (0.22)0.47 (0.43)Non-MTC−0.57 (0.28)Non-MTC−0.36 (0.63)145.73 (1.35)−23.15 (1.31)20.17 (2.25)5.91 (1.22)
  30.48 (0.56)1.86 (0.69)0.78 (0.060)1.68 (0.59)0.04 (0.68)0.05 (0.67)1.8−12.15 (5.51)−29.24 (3.49)5.91 (2.36)−6.80 (1.31)
  4Non-MTC10.52 (1.68)Non-MTCNon-MTCNon-MTC10.52 (1.68)100−14.34 (1.76)−19.95 (3.06)31.45 (2.14)−1.67 (3.88)
Mid-test (week 4)
  11.44 (0.67)Non-MTCNon-MTCNon-MTCNon-MTC1.44 (0.67)100−14.51 (1.60)−27.83 (2.23)20.61 (1.60)−7.00 (1.67)
  20.13 (0.66)1.56 (0.85)0.07 (0.64)0.29 (0.62)−0.25 (0.58)0.21 (1.04)46.30.65 (2.25)−51.98 (6.67)26.07 (4.53)2.38 (2.83)
  31.09 (0.70)1.35 (0.78)0.67 (0.69)1.92 (0.70)1.39 (0.71)0.68 (0.69)1.4−9.88 (4.86)−28.41 (4.11)7.94 (2.77)−3.56 (1.84)
  4Non-MTC8.30 (1.47)Non-MTCNon-MTCNon-MTC8.30 (1.47)100−16.96 (1.60)−16.44 (1.90)25.36 (2.02)−2.12 (0.96)
Post-test (week 8)
  11.84 (0.68)NON-MTCNon-MTCNon-MTCNon-MTC1.84 (0.68)100−11.42 (1.44)−27.97 (2.10)22.39 (2.42)−0.95 (2.38)
  20.21 (0.57)1.42 (0.68)−0.11 (0.56)0.11 (0.53)−0.55 (0.47)0.12 (0.91)59.40.07 (2.18)−48.41 (5.80)26.12 (4.46)−2.92 (3.48)
  30.77 (0.77)1.47 (0.72)0.98 (0.78)1.54 (0.73)0.89 (0.87)0.82 (0.88)1.3−11.38 (6.23)−29.41 (4.48)7.81 (2.99)−5.31 (1.08)
  4Non-MTC8.65 (1.42)Non-MTCNon-MTCNon-MTC8.65 (1.42)100−14.55 (2.21)−12.39 (2.24)20.33 (2.12)−6.33 (1.38)

 

↓  Table 3. Functional Outcome and Gait Measures
 
SubjectFGAWalk-12Stroke Impact Scale version 3ABC scaleGait speed (m/s) SDStep length (m) SD
MobilityParticipationPerceived recoveryLeftRight
**Missing data. Walk-12 formula = Transformed Walk-12 score = [(Raw Walk-12 score − 12)/48] × 100. Stroke Impact Scale subdomains [(Mean item score − 1)/4] × 100. FGA: functional gait assessment; ABC scale: Activities-Specific Balance Confidence Scale.
Baseline
  11760.4286.162.57573.10.30 (0.04)0.28 (0.05)0.14 (0.05)
  21147.9280.668.85065.60.75 (0.04)0.57 (0.03)0.45 (0.03)
  32410.42****70950.74 (0.05)0.57 (0.03)0.57 (0.03)
  41031.2583.3504034.50.18 (0.02)0.13 (0.02)0.27 (0.02)
Mid-test (week 4)
  11658.3386.178.16568.10.33 (0.04)0.29 (0.04)0.18 (0.05)
  21529.1794.496.95569.50.76 (0.04)0.59 (0.04)0.49 (0.04)
  31952.0877.834.47076.90.67 (0.05)0.55 (0.03)0.52 (0.03
  41181.2566.756.38056.30.21 (0.02)0.15 (0.03)0.30 (0.03)
Post-test (week 8)
  11564.5880.671.97568.80.30 (0.05)0.30 (0.06)0.12 (0.05)
  21710.4294.496.9**81.30.76 (0.05)0.57 (0.04)0.50 (0.03)
  32445.8388.937.575850.73 (0.04)0.62 (0.03)0.54 (0.03)
  41356.2572.228.135500.26 (0.02)0.17 (0.03)0.34 (0.02)