Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
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Case Report

Volume 000, Number 000, October 2025, pages 000-000


Ocular Syphilis in an Immunocompetent Patient: Through the Lens

Table

Table 1. Ocular Syphilis Cases in HIV-Negative Patients Published in the Years 2020 - 2024
 
Age/sexSymptomsStage of diagnosis
HIV: human immunodeficiency virus; M: male.
Nwaobi et al, 2023 [12]46/MPresented with vision loss in left eye and erythematous rashSecondary syphilis stage
Paulraj et al, 2020 [13]53/MPresented with blurred vision in both eyesSecondary syphilis
Kautz et al, 2024 [14]27/M; 47/M; 52/M; 43/MCase series of 4 patients presented with floaters, blurry vision and central vision lossLatent syphilis
Xu et al, 2022 [6]Case series with 16 HIV negative cases, median age 51, 7 males and 9 femalesVisual acuity loss, blindness, blepharoptosis, blurred vision3 cases were in the early syphilis stage, 4 cases of late syphilis, and 10 cases of an unidentified stage
Jahnke et al, 2021 [15]Case series of four patients with 2 HIV-negative 27/M; 53/MDiplopia, vertigo, and headache and left eye vision loss1 case in primary syphilis stage, 1 case in tertiary stage, 1 case in secondary stage, 1 case in unidentified stage
Koksali et al, 2023 [16]Case series of 10 patients with 8 of them HIV-negativeVision loss1 case in primary syphilis, 4 cases in secondary syphilis stage, 5 cases in latent syphilis stage
Kabanovski et al, 2022 [17]Case series of 4 HIV-negative patients, median age of 43, with 2 males and 2 femalesPhotopsia, vision loss, blurry vision2 cases in the secondary syphilis stage and 2 cases in an unidentified stage