Journal of Medical Cases, ISSN 1923-4155 print, 1923-4163 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Med Cases and Elmer Press Inc
Journal website https://jmc.elmerpub.com

Case Report

Volume 16, Number 9, September 2025, pages 387-391


Life-Threatening Calcium Chloride Ingestion

Figure

Figure 1.
Figure 1. Sequential measurement of (upper; Y-axis is a logarithmic scale) serum levels of intact parathyroid hormone (pg/mL) and 24-h urine calcium and phosphorus (mg in 24-h urine), and (lower) serum calcium and phosphorus (mg/dL). Notably, the initial parathyroid hormone level, indicated by the downward arrow, was much lower than the levels measured after recovery. This result suggests that parathyroid hormone levels decreased immediately after CaCl2 ingestion, accompanied by increased renal calcium and decreased renal phosphorus excretion. In parallel, serum calcium and phosphorus levels gradually normalized by the fourth day of hospitalization. The normal reference ranges were as follows: 24-h urine phosphorus < 250 mg (females), 24-h urine calcium 400 - 1,300 mg, and serum intact parathyroid hormone 15 - 65 pg/mL. Reference values for serum calcium and phosphorus are shown in Table 1. Creatinine clearance, measured by 24 h urine on day 2, 3, and 6, was 41.7, 37.5, and 46.7 mL/min, respectively.

Table

Table 1. Initial Laboratory Findings
 
Laboratory testsResultsReference value
aNote the marked hypercalcemia. The blood sample was collected 2 h after CaCl2 ingestion. BUN: blood urea nitrogen; CBC: complete blood count; RBC: red cell count; WBC: white cell count.
CBC
  WBC (/µL)18,5404,000 - 10,000
  RBC (× 106/µL)4.594.0 - 5.5
  Hemoglobin (g/dL)14.312 - 16
  Hematocrit (%)4236 - 48
  Platelets (× 103/µL)308130 - 450
  Neutrophil (seg) (%)80.940 - 72
  Lymphocytes (%)13.917.0 - 45.0
  Monocytes (%)4.94 - 12
Blood chemistry
  Total protein (g/dL)7.65.7 - 8.2
  Albumin (g/dL)4.53.2 - 4.8
  Glucose (mg/dL)10374 - 100
  BUN (mg/dL)129.0 - 26.0
  Creatinine (mg/dL)0.960.5 - 1.1
  Bilirubin, total (mg/dL)1.130.3 - 1.2
  Aspartate transaminase (U/L)308 - 34
  Alanine transferase (U/L)1910 - 45
  Alkaline phosphatase (U/L)5630 - 120
  Calcium, total (mg/dL)19.4a8.8 - 10.6
  Phosphorus (mg/dL)6.62.4 - 6.1
  Lactate dehydrogenase (U/L)252140 - 271
  Creatine phosphokinase (U/L)1690 - 145
  C-reactive protein (mg/dL)0.080.01 - 1.0
  Sodium (mEq/L)137132 - 150
  Potassium (mEq/L)3.53.5 - 5.5
  Chloride (mmol/L)10592 - 110