An Unusual Case of Pancreatic Adenocarcinoma Metastasis to the Trapezium Bone

Abstract

Pancreatic adenocarcinoma is an aggressive malignancy that accounts for over 90% of pancreatic cancers. It is associated with a poor prognosis and a 5-year survival rate of less than 10%. In 2023, there were an estimated 64,050 new cases of pancreatic cancer and 50,550 related deaths. Common sites of metastasis include the liver, lungs, lymph nodes, and peritoneal cavity. While bone metastases can occur, metastatic disease involving the bones of the hand is exceedingly rare. In this report, we present a case of metastatic pancreatic cancer involving the trapezium bone of the hand, along with a review of the literature.